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The perturbed glutamine-glutamate metabolism induced neurotransmitter imbalance and created an immune-inhibitory state with increased gamma-aminobutyric acid/glutamate ratio, thus facilitating efficient viral replication both in JEV-infected neurons and the brain of JEV-infected mice

These patches may appear as freckles or larger, irregularly bordered dark spots known as macules

Strausfeld and his trainees analyzed the role of interneurons in various parts of the insect nervous system